Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Szucs, TD; Berger, K; März, W; Schäfer, JR.
Cost effectiveness of pravastatin in secondary coronary prevention in patients with myocardial infarct or unstable angina in Germany. An analysis on the basis of the LIPID trial
Herz. 2000; 25(5): 487-494.
Doi: 10.1007/PL00001961
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- Co-Autor*innen der Med Uni Graz
- März Winfried
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- Abstract:
- Secondary coronary prevention with lipid lowering drugs has become a major issue in health policy formulation due to the large upfront investment in drug therapy. The recently completed LIPID trial with pravastatin in secondary prevention immediately raise the question whether pravastatin might be cost-effective in Germany. We conducted a cost-effectiveness analysis from the perspective of third party payers. The following costs were included in the analysis: daily treatment costs of pravastatin, non-fatal myocardial infarction, coronary bypass operations and stroke. Life years gained were obtained by applying the declining exponential approximation of life expectancy. All calculations were standardized to 1,000 treated patients. The net costs of treating 1,000 patients (i.e. drug costs minus the costs of sequelae and interventions) are DM 8.4 Mio. In addition, a total of 405 life years may be saved through treatment. The corresponding cost-effectiveness of pravastatin treatment is DM 20,674,-(DM 17,314,-, discounted by 3% p.a.).
- Find related publications in this database (using NLM MeSH Indexing)
- Angina, Unstable - drug therapy
- Anticholesteremic Agents - economics
- Clinical Trials - economics
- Coronary Disease - economics
- Cost-Benefit Analysis - economics
- Costs and Cost Analysis - economics
- Female - economics
- Germany - economics
- Humans - economics
- Hydroxymethylglutaryl-CoA Reductase Inhibitors - economics
- Life Expectancy - economics
- Male - economics
- Middle Aged - economics
- Myocardial Infarction - drug therapy
- Pravastatin - economics
- Quality of Life - economics
- Find related publications in this database (Keywords)
- cost analysis
- cost-effectiveness
- lipids
- status
- pravastatin
- coronary heart disease
- myocardial infarction
- unstable angina pectoris