Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Hutterer, G; Perrotte, P; Gallina, A; Walz, J; Jeldres, C; Traumann, M; Suardi, N; Saad, F; Bénard, F; Valiquette, L; McCormack, M; Graefen, M; Montorsi, F; Karakiewicz, PI.
Body mass index does not predict prostate-specific antigen or percent free prostate-specific antigen in men undergoing prostate cancer screening.
Eur J Cancer. 2007; 43(7):1180-1187
Doi: 10.1016/j.ejca.2007.01.005
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- Hutterer Georg
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- Abstract:
- OBJECTIVES: Body mass index (BMI) may alter serum prostate specific antigen (PSA) and percent free PSA (%fPSA) and may mask the risk of prostate cancer. We investigated the relationship between BMI and PSA or %fPSA. MATERIALS AND METHODS: Height, weight, PSA and %fPSA were assessed in 616 consecutive screened men without prostate cancer. Continuously coded and categorised BMI was studied. Statistical analyses consisted of ANOVA, linear regression, bivariate and partial correlations. RESULTS: Median age was 57 years. Median PSA was 1.0 and median %fPSA was 26. Median BMI was 25.8 kg/m(2). Neither continuously coded nor categorised BMI correlated with either PSA or %fPSA in unadjusted or age-adjusted analyses (all p values > or = 0.3). CONCLUSIONS: Body mass index does not affect PSA or %fPSA in men without known prostate cancer, who undergo prostate cancer screening. Therefore, PSA or %fPSA-based screening or early detection efforts do not require an adjustment for BMI.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Age Distribution -
- Aged -
- Analysis of Variance -
- Body Mass Index -
- Cohort Studies -
- Humans -
- Male -
- Mass Screening - methods
- Middle Aged - methods
- Obesity - blood
- Overweight - physiology
- Prostate-Specific Antigen - blood
- Prostatic Neoplasms - blood
- Risk Factors - blood
- Find related publications in this database (Keywords)
- body mass index
- prostate cancer
- prostate-specific antigen