Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Bader, AA; Petru, E; Winter, R.
Long-term follow-up after neoadjuvant chemotherapy for high-risk cervical cancer during pregnancy.
Gynecol Oncol. 2007; 105(1):269-272
Doi: 10.1016/j.ygyno.2007.01.009
(- Case Report)
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- Leading authors Med Uni Graz
- Bader Arnim
- Co-authors Med Uni Graz
- Petru Edgar
- Winter Raimund
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- Abstract:
- BACKGROUND: We report on a patient with a high-risk cervical cancer during pregnancy treated with neoadjuvant chemotherapy (NACT) followed by radical surgery. CASE: A 38-year-old woman was diagnosed with FIGO stage IIA cervical cancer at 19 weeks' gestation. She received four cycles of cisplatin (50 mg/m2) and vincristine (1 mg/m2) at 3-week intervals starting at 23 weeks' gestation. A cesarean section with radical hysterectomy and pelvic lymphadenectomy was performed at 33 weeks, delivering a 1920 g male newborn. Histology showed a poorly differentiated squamous cell carcinoma with lymph vascular invasion and pelvic lymph node metastases. The patient received three further cycles of chemotherapy. Both mother and child are healthy at 80 months after the primary diagnosis. CONCLUSION: NACT followed by radical surgery may be effective in selected patients with invasive cervical cancer during pregnancy.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Antineoplastic Combined Chemotherapy Protocols - therapeutic use
- Carcinoma, Squamous Cell - drug therapy
- Cesarean Section - drug therapy
- Cisplatin - administration and dosage
- Female - administration and dosage
- Humans - administration and dosage
- Hysterectomy - administration and dosage
- Lymph Node Excision - administration and dosage
- Neoadjuvant Therapy - administration and dosage
- Neoplasm Staging - administration and dosage
- Pregnancy - administration and dosage
- Pregnancy Complications, Neoplastic - drug therapy
- Risk Factors - drug therapy
- Uterine Cervical Neoplasms - drug therapy
- Vincristine - administration and dosage