Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Odes, HS; Madar, Z; Trop, M; Namir, S; Gross, J; Cohen, T.
Pilot study of the efficacy of spent grain dietary fiber in the treatment of constipation.
Isr J Med Sci. 1986; 22(1): 12-15.
[OPEN ACCESS]
Web of Science
PubMed
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Trop Marija
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Abstract:
- Spent grain is the crude fiber obtained by decanting the fermented distillate of barley. The spent grain was processed to yield dietary fiber composed of: cellulose and hemicellulose 65.6% (by weight), lignin 5.2%, pectin 2.2%, protein 10.9% and lipid 8.0%. Biscuits and scones were prepared by 25% substitution of wheat flour by fiber, yielding 7 to 8 g fiber per biscuit/scone. Nineteen ambulatory patients with chronic, laxative-dependent constipation were treated in a pilot study for 4 weeks with 20 to 25 g fiber daily. Fifteen patients (79%) showed improvement in some or all of five factors, while four patients were largely unresponsive to fiber. Specific symptoms improved as follows: bowel movement frequency in 15 patients (79%), flatulence in 12 (63%), abdominal pain in 10 (53%), stool consistency in 8 (42%) and laxative dependence in 14 (74%). A 4-week post-treatment follow-up showed a return to prefiber status in 11 of 13 improved subjects. This preliminary study suggests a role for spent grain fiber in the treatment of constipated patients, and a comparative study with placebo and wheat fiber is now warranted.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Animals -
- Cathartics - physiology
- Cereals - physiology
- Constipation - diet therapy
- Defecation - diet therapy
- Dietary Fiber - therapeutic use
- Feces - therapeutic use
- Female - therapeutic use
- Gases - therapeutic use
- Hordeum - therapeutic use
- Humans - therapeutic use
- Intestines - physiopathology
- Male - physiopathology
- Middle Aged - physiopathology
- Pilot Projects - physiopathology
- Rats - physiopathology