Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Trop, M; Tompkins, RG; Schiffrin, EJ; Carter, EA; Burke, JF.
Core body temperature responses immediately after cutaneous thermal injury in rats.
J Burn Care Rehabil. 1992; 13(6): 632-638.
Doi: 10.1097/00004630-199211000-00005
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- Abstract:
- Internal temperatures were continuously measured in rats that received 20% or 40% body surface area cutaneous scald injuries in 25 degrees C and 38.5 degrees C environments. In animals that received thermal injuries in the 25 degrees C environment, intraperitoneal, intraesophageal, and intrarectal temperatures rapidly rose to 40 degrees C within 5 minutes but returned to normal values within 15 minutes after injury. When 20% body surface area injuries were induced in a 25 degrees C environment, all of the animals survived. In the 25 degrees C environment, neither acute core body temperature elevations nor use of fluid resuscitation predicted survival. In contrast, in a 38.5 degrees C environment core body temperatures rapidly exceeded 41 degrees C with the 20% injury, and all of the animals died within minutes in spite of fluid resuscitation. These studies suggest that the ambient environmental temperature may significantly influence a thermally injured animal's ability to rapidly eliminate absorbed heat of injury and result in an elevated core body temperature, which may contribute to the immediate lethality of the injury.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Body Temperature - physiology
- Body Temperature Regulation - physiology
- Burns - mortality Burns - physiopathology Burns - therapy
- Female -
- Fluid Therapy -
- Rats -
- Temperature -
- Thermometers -
- Time Factors -