Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Uhrig, S; Geigl, JB; Speicher, MR.
Genetic counseling in multiple pregnancies
Gynakol Geburtshilfliche Rundsch. 2007; 47(1): 9-13.
Doi: 10.1159/000098120
PubMed
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- Führende Autor*innen der Med Uni Graz
- Speicher Michael
- Uhrig Sabine
- Co-Autor*innen der Med Uni Graz
- Geigl Jochen Bernd
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- Abstract:
- Genetic counseling in cases of multiple pregnancies shows marked differences compared to singleton pregnancies. The rising rate of multiple pregnancies and its association with advanced maternal age has expanded the need for prenatal diagnosis in twins and higher-order gestations. However, the request for invasive prenatal diagnostic procedures often differs in multiple and singleton pregnancies. This is in particular true when the multiple pregnancy occurred after assisted reproductive technology. In case of twin pregnancies, the distinction between a mono- and dizygotic pregnancy may facilitate the decision about obtaining a single or two samples. Discordant anomalies pose a special problem. Discordant anomalies are in rare instances even observed in monozygotic pregnancies. Here, we summarize the clinical, analysis-related and ethical problems regarding genetic counseling in multiple pregnancies.
- Find related publications in this database (using NLM MeSH Indexing)
- Chromosome Aberrations -
- Female -
- Genetic Counseling -
- Genetic Screening -
- Humans -
- Infant, Newborn -
- Pregnancy -
- Pregnancy, Multiple - genetics
- Prenatal Diagnosis - genetics
- Twins, Dizygotic - genetics
- Twins, Monozygotic - genetics