Medizinische Universität Graz - Research portal
Selected Publication:
Jaeger, BR; Goehring, P; Schirmer, J; Uhrig, S; Lohse, P; Kreuzer, E; Reichart, B; Seidel, D.
Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach.
Ther Apher. 2001; 5(4): 252-259.
Doi: 10.1046/j.1526-0968.2001.00350.x
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- Co-authors Med Uni Graz
- Uhrig Sabine
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- Abstract:
- Hypercoagulability is a key contributor to acute cardiovascular syndromes and to various microcirculatory disorders. The use of heparin-mediated extracorporeal low-density lipoprotein/fibrinogen precipitation (HELP) apheresis makes a controlled, immediately effective reduction of clotting factors possible, and induces subsequent positive effects on plasma viscosity, erythrocyte aggregation, and microcirculation. Oxygen supply to an ischemic artery can thus be increased without hemodilution, qualifying the HELP system as a possible therapeutic tool in the treatment of acute cardiovascular syndromes and microcirculatory disorders.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Blood Coagulation - physiology
- Blood Coagulation Disorders - therapy
- Blood Coagulation Factors - analysis
- Cardiovascular Diseases - therapy
- Coronary Arteriosclerosis - prevention and control
- Coronary Thrombosis - prevention and control
- Female - prevention and control
- Hemorheology - prevention and control
- Humans - prevention and control
- Hypercholesterolemia - therapy
- Male - therapy
- Middle Aged - therapy
- Plasmapheresis - methods
- Find related publications in this database (Keywords)
- atherosclerosis
- cardiovascular diseases
- cholesterol
- coagulation
- fibrinogen
- low-density lipoprotein apheresis
- thrombolysis