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Selected Publication:
SCHNEDITZ, D; PROBST, W; KUBISTA, H; BINSWANGER, U.
BLOOD-VOLUME MONITORING BY ULTRASONIC MEASUREMENT IN THE EXTRACORPOREAL BLOOD CIRCUIT
NIEREN HOCHDRUCK. 1991; 20(11): 649-652.
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- Leading authors Med Uni Graz
- Schneditz Daniel
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- Abstract:
- The first part of the investigation deals with the determination of relative blood volume changes (DELTA-V(b)) during hemodialysis (HD) with acetate or bicarbonate as buffer substrate. The method to document DELTA-V(b) is based upon noninvasive, on-line monitoring of blood water concentration (BWC) by ultrasonic means. Results were related to the ultrafiltration rate during treatment. There was no significant difference concerning DELTA-V(b) between the two different dialysis modalities. However, a significant fall in mean arterial pressure (MAP) during acetate dialysis was observed. In the second part of this work blood volume (V(b)) and cardiac output (CO) was calculated from the dilution of a pulse injection of 50 ml saline. The indicator was injected into the venous part of the blood line while its dispersion was traced in the arterial blood line. Mean delay between injection and appearance of the indicator and mean duration of the dilution peak at the measuring site was 17 and 30 s, respectively. Flow between injection and measuring site representing CO was calculated from the area of the first dilution peak. V(b) Was calculated from the change of BWC before and after dilution. For triplicate determination in 6 patients, variation-coefficients for the determination Of V(b) ranged from 1-27% (mean 14%) and from 2-8% (mean 4%) for the estimation of CO. The values were not validated but with possible technical improvements the method could be useful for investigation. of hemodynamics during HD treatments.
- Find related publications in this database (Keywords)
- ACETATE
- BICARBONATE
- SALINE DILUTION
- BLOOD VOLUME
- CARDIAC OUTPUT
- HEMODIALYSIS