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Zaluska, WT; Schneditz, D; Kaufman, AM; Morris, AT; Levin, NW.
Relative underestimation of fluid removal during hemodialysis hypotension measured by whole body bioimpedance.
ASAIO J. 1998; 44(6):823-827 Doi: 10.1097/00002480-199811000-00011
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Schneditz Daniel
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Abstract:
Whole body bioimpedance is considered helpful in monitoring the removal of excess body water by ultrafiltration in hemodialysis patients. In this study, the cumulative, estimated decrease in extracellular volume (V(est)) modeled from whole body bioimpedance data was compared with measured volume (Vmeas) removed by ultrafiltration (UFR = 1.01 +/- 0.31 L/hr) in 12 patients during 36 high efficiency hemodialysis treatments. In the mean, estimated (V(est) = 3.0 +/- 1.4 L) and measured volumes (Vmeas = 3.4 +/- 1.1 L) correlated linearly: V(est) = 1.05 x Vmeas - 0.60, r2 = 0.68. Patients developed hypotension in half the treatments. Except for a larger decrease in systolic blood pressures in hypotensive (34 +/- 24 mmHg) vs. stable (14 +/- 15 mmHg) treatments, patient and treatment characteristics were not different between groups. However, at the end of hemodialysis, the difference V(est) - Vmeas was -0.8 +/- 0.9 L in hypotensive, and only 0.1 +/- 0.4 L in stable patients (p < 0.05). The difference between V(est) and Vmeas can be explained by a predominant removal of excess body water from central body compartments such as the trunk and the central blood volume during hypotension. These compartments are not adequately measured by whole body bioimpedance techniques. However, this information could be helpful in identifying patients with delayed peripheral fluid removal that may occur when either target weight is too low or UFR rates are too high.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Blood Volume -
Body Water - metabolism
Electric Impedance - metabolism
Humans - metabolism
Hypotension - etiology
Middle Aged - etiology
Renal Dialysis - adverse effects
Ultrafiltration - adverse effects

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