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FRUHWALD, FM; EBER, B; SCHUMACHER, M; ZWEIKER, R; POKAN, R; KAUFMANN, P; KLEIN, W.
CLINICAL IMPACT OF SILENT-MYOCARDIAL-ISCHEMIA IN THE EARLY POSTINFARCTION PERIOD
HERZ KREISLAUF. 1995; 27(11): 363-365.
Web of Science

Leading authors Med Uni Graz: Fruhwald Friedrich
Co-authors Med Uni Graz: Zweiker Robert
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Abstract:: To investigate the clinical impact of silent myocardial ischemia (SMI), we investigated 21 patients (18 m, 3 f; mean age 64 +/- 9 years) showing an acute myocardial infarction (AMI, defined by pain and typical EGG) by 48-h Holter-monitoring starting 9 +/- 2 h after onset of AMI. All patients received intravenously nitroglycerine and heparin as well as oral aspirin. 15 patients had systemic thrombolysis, 6 were defibrillated. 12 patients showed signs of SMI by horizontal or downsloping ST-segment depression, mean duration was 101 +/- 50 min. Half of these patients got systemic thrombolysis. Subgroup analysis showed a trend to shorter ischemia in patients with thrombolysis, but the difference was not statistically significant [75 +/- 11 (median 73) vs. 101 +/- 85 min (median 95)]. 3 months after AMI, an upright bicycle test was performed. It showed comparable results in both SMI-positive and SMI-negative groups regarding maximal workload (95 +/- 11 vs. 90 +/- 21 W,n.s.), maximal systolic blood pressure (161 +/- 20 vs. 165 +/- 22 mmHg, n.s.) and maximal heart rate (125 +/- 14 vs. 130 +/- 10 beats/min, n.s.). Within the first year after AMI, cardiac events occurred in both groups. Conclusions: Silent myocardial ischemia represents a common finding in the early postinfarction phase but it seems to have no prognostic significance.
Find related publications in this database (Keywords): SILENT MYOCARDIAL ISCHEMIA; ACUTE MYOCARDIAL INFARCTION; HOLTER-MONITORING; PROGNOSIS