Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Bonelli, RM; Aschoff, A; Jirikowski, G.
Cerebrospinal fluid tissue transglutaminase in vascular dementia.
J Neurol Sci. 2002; 203-204(8): 207-209.
Doi: 10.1016/S0022-510X(02)00292-7
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- Führende Autor*innen der Med Uni Graz
- Bonelli Raphael
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- Abstract:
- The enzyme tissue transglutaminase (tTG), an indicator of acute cell death, is found in brains of Alzheimer's and Huntington's disease patients. tTG, as a specific marker for apoptosis, may therefore be a powerful biochemical marker of the acute degenerating process in vivo and may be useful in discrimination between vascular dementia (VaD) and Alzheimer's disease (AD). It may serve as completion of CSF analysis in diagnosis of dementing disorders and be a simple way of assessing the efficacy of possible new anti-apoptotic drugs.
- Find related publications in this database (using NLM MeSH Indexing)
- Alzheimer Disease - cerebrospinal fluid
- Biological Markers - cerebrospinal fluid
- Dementia, Vascular - cerebrospinal fluid
- Humans - cerebrospinal fluid
- Transglutaminases - cerebrospinal fluid
- tau Proteins - metabolism
- Find related publications in this database (Keywords)
- vascular dementia
- Alzheimer's disease
- tissue transglutaminase
- apoptosis
- tau protein