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Barth, A; Arnold, M; Mattle, HP; Schroth, G; Remonda, L.
Contrast-enhanced 3-D MRA in decision making for carotid endarterectomy: a 6-year experience.
Cerebrovasc Dis. 2006; 21(5-6): 393-400. Doi: 10.1159/000091964
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Barth Alain
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Abstract:
BACKGROUND: Systematic need for angiography in diagnosis of carotid artery stenosis and indication of surgical therapy is still debated. Noninvasive imaging techniques such as MR angiography (MRA) or CT angiography (CTA) offer an alternative to digital subtraction angiography (DSA) and are increasingly used in clinical practice. In this study, we present the radiological characteristics and clinical results of a series of patients operated on the basis of combined ultrasonography (US)/MRA. METHODS: This observational study included all the patients consecutively operated for a carotid stenosis in our Department from October 1998 to December 2004. The applied MRA protocol had previously been established in a large correlation study with DSA. DSA was used only in case of discordance between US and MRA. The preoperative radiological information furnished by MRA was compared with intraoperative findings. The outcome of the operation was assessed according to ECST criteria. RESULTS: Among 327 patients, preoperative MRA was performed in 278 (85%), DSA in 44 (13.5%) and CT angiography in 5 (1.5%). Most of DSA studies were performed as emergency for preparation of endovascular therapy or for reasons other than carotid stenosis. Eleven additional DSA (3.3%) complemented US/MRA, mostly because diverging diagnosis of subocclusion of ICA. No direct morbidity or intraoperative difficulty was related to preoperative MRA. Combined mortality/major morbidity rate was 0.9% (3 patients) and minor morbidity rate 5.5% (18 patients). CONCLUSIONS: This observational study describes a well-established practice of carotid surgery and supports the exclusive use of non invasive diagnostic imaging for indicating and deciding the operation.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Aged, 80 and over -
Carotid Stenosis - diagnosis
Cohort Studies - diagnosis
Contrast Media - diagnosis
Decision Making - diagnosis
Endarterectomy, Carotid - adverse effects
Female - adverse effects
Humans - adverse effects
Imaging, Three-Dimensional - adverse effects
Magnetic Resonance Angiography - adverse effects
Male - adverse effects
Middle Aged - adverse effects
Organometallic Compounds - diagnostic use
Patient Selection - diagnostic use
Treatment Outcome - diagnostic use

Find related publications in this database (Keywords)
carotid artery
carotid stenosis
contrast-enhanced
3-D magnetic resonance angiography
endarterectomy
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