Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Vukicevic, S; Stavljenic, A; Boll, T; Vujicic, G; Degenhardt, C; Cervar, M; Krempien, B.
Effects of parathyroidectomy on tissue calcium, phosphorus, magnesium, and copper concentrations in aluminum-loaded uremic rats.
Biol Trace Elem Res. 1989; 22(1): 45-53.
Doi: 10.1007/BF02917415
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Cervar-Zivkovic Mila
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Rats were subjected to a two-stage 5/6 nephrectomy and treated with Al for 2 and 4 wk with a cumulative dose of 4.2 and 8.4 mg of Al, respectively. Other animals were parathyrectomized (PTx) and loaded with 8.4 mg of Al for 4 wk. Total Al, Ca, P, Mg, and Cu contents were analyzed in the liver, kidney, and bone by inductively coupled plasma atomic emission spectrometry (ICP-AES). The results showed that Al given to growing uremic rats significantly increased the content of Al in the liver, kidney, and bone. Moreover, Al treatment increased the liver and kidney Ca levels and decreased the Ca and P values in bone. Previous parathyroidectomy significantly reduced Al accumulation within organs and changes in the Ca and P levels in the bone, liver, and kidney. The result was not influenced by different degrees of renal failure.
- Find related publications in this database (using NLM MeSH Indexing)
- Aluminum - pharmacology
- Animals - pharmacology
- Bone and Bones - metabolism
- Calcium - metabolism
- Copper - metabolism
- Kidney - metabolism
- Liver - metabolism
- Magnesium - metabolism
- Nephrectomy - metabolism
- Parathyroid Glands - physiology
- Phosphorus - metabolism
- Rats - metabolism
- Rats, Inbred Strains - metabolism
- Uremia - metabolism