Medizinische Universität Graz - Research portal
Selected Publication:
Mallin, W; Eber, E; Semmelrock, HJ; Zach, M.
Determination of theophylline serum level: comparison between a rapid test (enzyme-immuno-chromatography) and conventional fluorescence polarization immunoassay
Pneumologie. 1990; 44(8):967-969
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- Co-authors Med Uni Graz
- Eber Ernst
- Semmelrock Hans-Jürgen
- Zach Maximilian
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- Abstract:
- To evaluate the reliability and accuracy of a rapidly performed enzyme immunochromatography method for measuring the serum concentration of theophylline, we compared it with a conventional technique (fluorescence-polarisation immunoassay). We investigated 103 venous blood samples from children and adolescents with bronchial asthma, medicated with sustained-release theophylline preparations. There was a highly significant correlation of the measured values; with a few exceptions, the individual values scattered only narrowly around the regression line. Based on this close correlation, the investigated enzyme immunochromatography test can be recommended for rapid theophylline serum level determinations in clinical practice.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Asthma - blood
- Child - blood
- Delayed-Action Preparations - blood
- Fluorescence Polarization Immunoassay - blood
- Humans - blood
- Immunoenzyme Techniques - blood
- Theophylline - administration and dosage