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Kurz, H; Eber, E; Frischer, T; Götz, M; Horak, E; Riedler, J; Schmitzberger, R; Zach, M; Arbeitsgruppe Pneumologie und Allergologie der Osterreichischen Gesellschaft für Kinder- und Jugendheilkunde (OGKJ); Arbeitsgruppe Pädiatrische Pneumologie und Allergologie der Osterreichischen Gesellschaft für Pneumologie (OGP).
Long-acting beta-2 agonists in pediatric asthma therapy--friend or foe
Wien Klin Wochenschr. 2006; 118(11-12):362-364
Doi: 10.1007/s00508-006-0607-0
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- Co-authors Med Uni Graz
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Eber Ernst
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Zach Maximilian
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- Abstract:
- Recent publications suggest that long-acting beta-2 agonists (LABAs) increase the risk for death in asthma. The American Food and Drug Administration (FDA) published a relevant alert in 2005. In the currently valid Austrian consensus guidelines for drug therapy of bronchial asthma in children and adolescents, LABAs are only recommended as add-on therapy in those patients whose asthma is not sufficiently controlled by inhaled corticosteroids (ICS) alone. LABAs have no established role in earlier steps of the therapeutic algorithm; consequently, the prescription of ICS-LABA combinations for initial treatment of paediatric asthma is not supported by these consensus treatment guidelines.
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