Medizinische Universität Graz - Research portal
Selected Publication:
Graninger, WB; Hassfeld, W; Pesau, BB; Machold, KP; Zielinski, CC; Smolen, JS.
Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.
J Rheumatol. 1991; 18(10):1621-1622
(- Case Report)
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- Leading authors Med Uni Graz
- Graninger Winfried
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- Abstract:
- The development of systemic lupus erythematosus (SLE) after 38 months of therapy with recombinant human interferon gamma (rIFN-gamma) was observed in a patient with rheumatoid arthritis. In addition to glomerulonephritis and a butterfly rash, previously negative tests for antinuclear, anti-dsDNA and anti-Sm antibodies became positive. We assume that rIFN-gamma induced the de novo development of SLE in our patient.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Antibodies - analysis
- Antibodies, Antinuclear - analysis
- Arthritis, Rheumatoid - complications Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - immunology
- Autoantigens - analysis
- Female -
- Glomerulonephritis - complications
- Humans -
- Immunoblotting -
- Interferon-gamma - adverse effects Interferon-gamma - therapeutic use
- Lupus Erythematosus, Systemic - chemically induced Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - immunology
- Recombinant Proteins - adverse effects Recombinant Proteins - therapeutic use
- Ribonucleoproteins, Small Nuclear -
- Time Factors -
- snRNP Core Proteins -
- Find related publications in this database (Keywords)
- RHEUMATOID ARTHRITIS
- INTERFERON GAMMA THERAPY
- SLE