Selected Publication:
Koeller, M; Kiener, H; Simonitsch, I; Aringer, M; Steiner, CW; Machold, K; Graninger, W.
Destructive lymphadenopathy and T-lymphocyte activation in adult-onset Still's disease.
Br J Rheumatol. 1995; 34(10):984-988
Doi: 10.1093/rheumatology/34.10.984
(- Case Report)
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- Co-authors Med Uni Graz
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Graninger Winfried
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- Abstract:
- Recurrent arthritis, fever and lymphadenopathy are symptoms of adult onset of Still's disease (AOSD). Differential diagnosis requires the exclusion of infections or malignant lymphomas. We report on a case of AOSD showing destructive lymphadenopathy, immunophenotyping of peripheral blood leucocytes revealed strong activation of T-lymphocytes. Bone marrow biopsy also showed an increase of lymphopoietic cells to 23%. Analysis of peripheral blood lymphocytes (PBL) after remission showed no remaining signs of activation. Analysis of lymphocyte activation by flow cytometry correlated with disease activity.
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Adult -
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Female -
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Humans -
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Lymphatic Diseases - etiology
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Lymphocyte Activation - etiology
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Still's Disease, Adult-Onset - complications
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T-Lymphocytes - immunology
- Find related publications in this database (Keywords)
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STILLS DISEASE
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LYMPHADENOPATHY
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LYMPHOCYTE ACTIVATION
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FLOW CYTOMETRY