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Selected Publication:

Koeller, M; Kiener, H; Simonitsch, I; Aringer, M; Steiner, CW; Machold, K; Graninger, W.
Destructive lymphadenopathy and T-lymphocyte activation in adult-onset Still's disease.
Br J Rheumatol. 1995; 34(10):984-988 Doi: 10.1093/rheumatology/34.10.984 (- Case Report)
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Co-authors Med Uni Graz
Graninger Winfried
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Abstract:
Recurrent arthritis, fever and lymphadenopathy are symptoms of adult onset of Still's disease (AOSD). Differential diagnosis requires the exclusion of infections or malignant lymphomas. We report on a case of AOSD showing destructive lymphadenopathy, immunophenotyping of peripheral blood leucocytes revealed strong activation of T-lymphocytes. Bone marrow biopsy also showed an increase of lymphopoietic cells to 23%. Analysis of peripheral blood lymphocytes (PBL) after remission showed no remaining signs of activation. Analysis of lymphocyte activation by flow cytometry correlated with disease activity.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Female -
Humans -
Lymphatic Diseases - etiology
Lymphocyte Activation - etiology
Still's Disease, Adult-Onset - complications
T-Lymphocytes - immunology

Find related publications in this database (Keywords)
STILLS DISEASE
LYMPHADENOPATHY
LYMPHOCYTE ACTIVATION
FLOW CYTOMETRY
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