Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schlembach, D; Scalera, F; Fischer, T; Marx, SG; Beinder, E; Garfield, RE.
Neurokinin B peptide serum levels are higher in normotensive pregnant women than in preeclamptic pregnant women.
Am J Obstet Gynecol. 2003; 189(5):1418-1422
Doi: 10.1067/S0002-9378(03)00775-0
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- Führende Autor*innen der Med Uni Graz
- Schlembach Dietmar
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- Abstract:
- OBJECTIVES: The purpose of this study was to examine neurokinin B levels in serum from preeclamptic and normotensive and to investigate the role of neurokinin B in preeclampsia. STUDY DESIGN: Peripheral and uterine venous blood neurokinin B levels were measured in 14 normotensive and 8 preeclamptic pregnant women by radioimmunoassay. RESULTS: Neurokinin B levels in normotensive women were 4.91 +/- 2.67 nmol/L in peripheral and 5.59 +/- 2.06 nmol/L in uterine blood. In pregnant women with preeclampsia, neurokinin B levels were 2.79 +/- 1.68 nmol/L and 3.20 +/- 1.55 nmol/L, respectively. Neurokinin B levels were significantly higher in normotensive women (P=.032 in peripheral and P=.006 in uterine blood). CONCLUSIONS: Neurokinin B serum levels were higher in normotensive women. Higher neurokinin B concentrations in normotensive pregnant women may be due to the advanced gestational age and/or the result of a negative interaction of other vasoactive substances. The role of neurokinin B in preeclampsia remains to be determined.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Case-Control Studies -
- Female -
- Gestational Age -
- HELLP Syndrome - blood
- Humans - blood
- Neurokinin B - blood
- Osmolar Concentration - blood
- Pre-Eclampsia - blood
- Pregnancy - blood
- Uterus - blood supply
- Find related publications in this database (Keywords)
- preeclampsia
- maternal serum
- tachykinin
- neurokinin B