Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Beinder, E; Schlembach, D.
Skin flux during reactive hyperemia and local hyperthermia in patients with preeclampsia.
Obstet Gynecol. 2001; 98(2):313-318
Doi: 10.1016/S0029-7844(01)01456-9
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- Co-Autor*innen der Med Uni Graz
- Schlembach Dietmar
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- Abstract:
- OBJECTIVE: To test the contribution of the endothelium to the maximum vasodilatation in patients with preeclampsia and healthy pregnant controls. METHODS: Laser-Doppler flowmetry, which is a noninvasive method for the continuous measurement of skin blood flow, was used to test the response of skin microcirculation to the above-mentioned stimuli in 14 patients with preeclampsia and 20 normotensive pregnant controls. RESULTS: In normotensive pregnant controls, the reactive hyperemic response after a 3-minute ischemia in the forearm reaches values of 77 +/- 16% of the maximum vasodilatation, which was induced by local hyperthermia of 42C. In patients with preeclampsia, this response was significantly (P <.05) reduced (43 +/- 9%). CONCLUSION: Vascular reactivity is altered in skin vessels of patients with preeclampsia in vivo. This alteration seems to be attributable mainly to the endothelium.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Endothelium, Vascular - physiopathology
- Female - physiopathology
- Forearm - physiopathology
- Humans - physiopathology
- Hyperemia - etiology
- Hyperthermia, Induced - etiology
- Ischemia - complications
- Laser-Doppler Flowmetry - complications
- Microcirculation - complications
- Pre-Eclampsia - physiopathology
- Pregnancy - physiopathology
- Skin - blood supply
- Vasodilation - blood supply