Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Fischer, T; Wallukat, G; Schneider, MP; Schlembach, D; Munz, W; Homuth, V.
HELLP syndrome in the 18th week of gestation in association with elevated angiotensin AT(1)-receptor autoantibodies.
Eur J Obstet Gynecol Reprod Biol. 2001; 97(2):255-257
Doi: 10.1016/S0301-2115(00)00534-0
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Schlembach Dietmar
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- Abstract:
- We present a 24-year-old woman with a twin pregnancy who was with a typical HELLP syndrome at the 18th week of pregnancy. One fetus was dead, while the other was severely growth retarded. Our patient had agonistic autoantibodies directed at the angiotensin AT(1)-receptor. Termination of the pregnancy proved necessary. This report is the first to our knowledge associating HELLP syndrome with angiotensin AT(1)-receptor antibodies. Since the antibodies may have a pathogenic significance, their removal could permit the prolongation of pregnancy in preeclamptic and HELLP syndrome patients.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Autoantibodies - blood
- Female - blood
- Fetal Death - immunology
- Fetal Growth Retardation - immunology
- Gestational Age - immunology
- HELLP Syndrome - immunology
- Humans - immunology
- Methylprednisolone - administration and dosage
- Pregnancy - administration and dosage
- Receptor, Angiotensin, Type 1 - administration and dosage
- Receptor, Angiotensin, Type 2 - administration and dosage
- Receptors, Angiotensin - immunology
- Twins - immunology
- Find related publications in this database (Keywords)
- HELLP syndrome
- preeclampsia
- AT(1)-receptor autoantibodies