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Holzer, A; Wolf, P; Legat, FJ; Kerl, H; Hofer, A.
Successful thalidomide therapy for actinic prurigo in a European woman.
J Dtsch Dermatol Ges. 2006; 4(11):961-964 Doi: 10.1111/j.1610-0387.2006.06125.x (- Case Report)
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Leading authors Med Uni Graz
Hofer Angelika
Co-authors Med Uni Graz
Kerl Helmut
Legat Franz
Wolf Peter
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Abstract:
Actinic prurigo is a rare, often difficult-to-treat, idiopathic photodermatosis. Actinic prurigo is divided into a hereditary form appearing in the Native American population and a sporadic form occurring in non-Native Americans. We present a 28-year-old Caucasian woman who developed typical clinical signs and symptoms of actinic prurigo, just as had her mother and grandmother. The patient and her mother were HLA-A24 and HLA-DR 4 with the subtype HLA-DRB1*0408. Based on clinical symptoms and the HLA pattern, the diagnosis of actinic prurigo was made. Treatment with thalidomide led to resolution of the disease. This case report of a Caucasian woman suffering from a hereditary form of actinic prurigo questions the established classification of actinic prurigo into a hereditary Native American form and a sporadic form occurring in the non-Native American population.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Adult -
Female -
Humans -
Photosensitivity Disorders - complications
Photosensitivity Disorders - diagnosis
Photosensitivity Disorders - drug therapy
Prurigo - complications
Prurigo - diagnosis
Prurigo - therapy
Thalidomide - therapeutic use
Treatment Outcome -

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