Gewählte Publikation:
Krachler, M; Domej, W; Irgolic, KJ.
Concentrations of trace elements in osteoarthritic knee-joint effusions.
BIOL TR ELEM RES 2000 75: 253-263.
Doi: 10.1385%2FBTER%3A75%3A1-3%3A253
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PubMed
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- Co-Autor*innen der Med Uni Graz
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Domej Wolfgang
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- Abstract:
- Concentrations of the 18 elements, barium (Ba), beryllium (Be), bismuth (Bi), calcium (Ca), cadmium (Cd), cesium (Cs), copper (Cu), lanthanum (La), lithium (Li), magnesium (Mg), molybdenum (Mo), lead (Pb), rubidium (Rb), antimony (Sb), tin (Sn), strontium (Sr), thallium (Tl), and zinc (Zn), were determined in the synovial fluids of osteoarthritic knee joints and in the corresponding sera of 16 patients by inductively coupled plasma-mass spectrometry. Knee-joint effusions have lower elemental concentrations than their corresponding sera. For the essential elements Ca, Cu, Mg, and Zn and for the nonessential and toxic elements Ba, Be, Bi, La, and Sb, this difference was highly significant. Strong positive correlations between concentrations in effusions and sera for the essential elements Cu and Mg and for the nonessential elements Cs, Li, Rb, and Sr could be established. The grade of localized hyperperfusion of the knee region in the blood pool phase of 99mTc HDP bone scan indicating inflammation did not correlate with any elemental concentration determined.
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Adult -
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Aged -
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Aged, 80 and over -
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Female -
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Humans -
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Male -
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Middle Aged -
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Osteoarthritis, Knee - metabolism
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Quality Control - metabolism
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Research Support, Non-U.S. Gov't - metabolism
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Spectrophotometry, Atomic - metabolism
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Synovial Fluid - chemistry
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Trace Elements - analysis
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osteoarthritis
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trace elements
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synovial fluid
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knee effusions
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serum
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ICP-MS