Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Salmhofer, W; Pierer, G; Auer-Grumbach, P; Soyer, HP; Kerl, H.
Cutaneous calciphylaxis in chronic renal failure
Hautarzt. 1995; 46(10):726-731
Doi: 10.1007%2Fs001050050330
(- Case Report)
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Salmhofer Wolfgang
- Co-Autor*innen der Med Uni Graz
- Kerl Helmut
- Soyer Hans Peter
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- Abstract:
- A case of a 53-year-old chronically uraemic female patient who suddenly developed widespread cutaneous necrosis on both thighs is presented. On the basis of the typical histopathological features a diagnosis of calciphylaxis was made and supported by elevated serum parathyroid hormone levels. Calciphylaxis is a rare and serious disease, mostly seen in uraemic patients subjected to chronic haemodialysis. Typical features are calcifying panniculitis and thrombosis of small to medium-sized blood vessels followed by necrosis of the skin. The poor prognosis is due to systemic calcifications of visceral organs. When acute cutaneous necrosis of the skin is encountered in patients with chronic uraemia calciphylaxis should always be considered as a possible cause in the differential diagnosis. Determination of the serum parathyroid hormone level is recommended.
- Find related publications in this database (using NLM MeSH Indexing)
- Biopsy -
- Calciphylaxis - pathology
- Diagnosis, Differential -
- Female -
- Humans -
- Kidney Failure, Chronic - pathology
- Middle Aged -
- Necrosis -
- Parathyroid Hormone - blood
- Renal Dialysis -
- Skin - pathology
- Thigh -
- Find related publications in this database (Keywords)
- Calciphylaxis
- Cutaneous Necrosis
- Renal Failure
- Hyperparathyroidism
- Anticardiolipin Antibodies