Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Breier, F; Oesterreicher, C; Brugger, S; Linkesch, W; Anegg, B; Jurecka, W.
Immunohistochemistry with monoclonal antibody against Candida albicans mannan antigen demonstrates cutaneous Candida granulomas as evidence of Candida sepsis in an immunosuppressed host.
DERMATOLOGY. 1997; 194(3): 293-296.
Doi: 10.1159/000246130
(- Case Report)
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Anegg Udo
- Linkesch Werner
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- Abstract:
- We report the occurrence of invasive Candida albicans infection with disseminated cutaneous Candida granulomas in a patient with aplastic anaemia after viral hepatitis. Fungal elements in a skin biopsy specimen were detected by PAS stain and identified as Candida sp. by immunohistochemistry directed against the C. albicans mannan surface antigen. Based on rapid diagnosis of Candida granuloma and by Candida-positive cultures of blood and swabs, systemic treatment with liposomal amphotericin B led to survival of the patient.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Amphotericin B - therapeutic use
- Anemia, Aplastic - virology
- Antibiotics, Antifungal - therapeutic use
- Antibodies, Fungal - therapeutic use
- Antibodies, Monoclonal - therapeutic use
- Antigens, Fungal - analysis
- Antigens, Surface - analysis
- Candida albicans - immunology
- Candidiasis - diagnosis
- Dermatomycoses - diagnosis
- Granuloma - diagnosis
- Hepatitis, Viral, Human - diagnosis
- Herpesviridae Infections - diagnosis
- Herpesvirus 4, Human - diagnosis
- Humans - diagnosis
- Immunocompromised Host - diagnosis
- Immunohistochemistry - diagnosis
- Male - diagnosis
- Mannans - analysis
- Polysaccharides, Bacterial - analysis
- Sepsis - diagnosis
- Find related publications in this database (Keywords)
- Candida granuloma
- bone marrow transplantation
- immunohistochemistry
- invasive fungal infection
- aplastic anaemia
- mannan antigen