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Wegscheider, BJ; El-Shabrawi, L; Weger, M; Ardjomand, N; Hermann, J; Aberer, E; El-Shabrawi, Y.
Adverse skin reactions to infliximab in the treatment of intraocular inflammation.
Eye. 2007; 21(4): 547-549.
Doi: 10.1038/sj.eye.6702262
(- Case Report)
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- Leading authors Med Uni Graz
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El-Shabrawi Yosuf
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Langner-Wegscheider Beate Julia
- Co-authors Med Uni Graz
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Aberer Elisabeth
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Ardjomand Navid
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El-Shabrawi-Caelen Laila
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Hermann Josef
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Weger Martin
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- Abstract:
- TNFalpha inhibitors are more widely used in the treatment of intraocular inflammation, thus ophthalmologists should become aware of possible adverse events, associated with this form of treatment. Herein we report two cases of cutaneous adverse events in uveitis patients treated with infliximab. In one patient, the primary outbreak of pustular psoriasis was observed after her third infusion. A second patient developed impetigo contagiosa induced by Staphylococcus aureus. Thus patients undergoing treatment with infliximab should be monitored carefully since dermal infections and pustular psoriasis, which may be triggered by streptococcal infection, may occur under this regime.
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Adolescent -
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Anti-Inflammatory Agents - adverse effects
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Antibodies, Monoclonal - adverse effects
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Chronic Disease - adverse effects
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Female - adverse effects
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Humans - adverse effects
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Impetigo - chemically induced
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Middle Aged - chemically induced
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Psoriasis - chemically induced
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Recurrence - chemically induced
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Tumor Necrosis Factor-alpha - antagonists and inhibitors
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Uveitis - drug therapy
- Find related publications in this database (Keywords)
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infliximab
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TNF alpha
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cutenous adverse side effects
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uveitis