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LITSCHER, G; SCHWARZ, G; PRIETL, B.
MIDDLE LATENCY AUDITORY-EVOKED POTENTIALS - NORMATIVE DATA AND RESULTS FROM INTENSIVE-CARE PATIENTS
EEG-EMG-Z ELEKTROENZ ELEKTROM. 1994; 25(4): 235-243.
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Leading authors Med Uni Graz: Litscher Gerhard
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Abstract:: Middle latency auditory evoked potentials were measured in 102 intensive care patients (mean age: 48.4 +/- 18.9 years) under the conditions of intensive care and the influence of biological variables. Latencies (V, NO, PO, Na, Pa), amplitudes (V, NO-PO, PO-Na, Na-Pa) and the amplitude ratio (PO-Na/Na-Pa) were evaluated. The results showed that middle latency AEP did not depend significantly on age. A temperature dependence was found for the latency of wave V (short latency AEP), which was prolonged as temperature decreased and for the amplitude Na-Pa which increased with decreasing temperature between 38.9 to 35.4-degrees-C. There was a significant association between the amplitude Na-Pa and PO2 (p = 0.017). Alterations of PCO2 in the range of 26 to 54 mm Hg did not influence the middle latency AEP. Also, kidney dysfunction (2.0 < creatinine < 4.5 mg/dl), liver dysfunction (2.0 < bilirubin < 6.3 mg/dl) and alterations of mean arterial pressure (range: 50-102 mm Hg) did not affect the AEP middle latencies and amplitudes significantly. Small increases in latencies and decreases in amplitude were seen in sedated patients. These results suggest that the combination of early AEP (acute phase) and middle latency AEP (post acute phase), with certain limitations, may be useful to monitor comatose patients.
Find related publications in this database (Keywords): MIDDLE LATENCY AUDITORY EVOKED POTENTIALS (MLAEP); MIDDLE LATENCY RESPONSE (MLR); INTENSIVE CARE PATIENTS; COMA; NORMATIVE DATA