Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Lackner, H; Urban, C; Benesch, M; Kerbl, R; Schwinger, W; Ring, E; Petritsch, P; Tscheliessnigg, KH; Margreiter, R.
Organ transplantation after oncologic therapy in childhood
MONATSSCHR KINDERHEILK. 1996; 144(2): 119-122.
Web of Science
- Führende Autor*innen der Med Uni Graz
- Lackner Herwig
- Co-Autor*innen der Med Uni Graz
- Benesch Martin
- Petritsch Peter
- Schwinger Wolfgang
- Tscheliessnigg Karlheinz
- Urban Ernst-Christian
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- Abstract:
- The improved results of cancer therapy justify a careful and critical analysis of delayed adverse sequelae. Chemotherapy, radiotherapy and surgery can variably damage different tissues and organs. In case of irreversible organ failure organ transplantation might be an option for some long-term survivors. We report on three patients, who received organ transplants following haemato-oncologic therapy. The first patient developed anthracycline-induced cardiomyopathy refractory to medical management 10 years after chemotherapy for B cell lymphoma and was treated successfully by heart transplantation. The second patient with Wilms tumor and Denys-Drash syndrome developed end - stage renal failure 10 months after discontinuation of therapy, which was treated by nephrectomy, hemodialysis and renal transplantation. The third patient underwent successful allogeneic bone marrow transplantation for congenital sideroblastic anemia but later developed chronic graft versus host disease of the liver inducing biliary cirrhosis. Five years after BMT a successful liver transplantation was performed.
- Find related publications in this database (Keywords)
- organ transplantation
- oncologic therapy
- childhood