Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Gallistl, S; Reitinger, T; Linhart, W; Muntean, W.
The role of inherited thrombotic disorders in the etiology of Legg-Calvé-Perthes disease.
J Pediatr Orthop. 1999; 19(1): 82-83.
Doi: 10.1097/00004694-199901000-00018
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- Führende Autor*innen der Med Uni Graz
- Gallistl Siegfried
- Co-Autor*innen der Med Uni Graz
- Linhart Wolfgang
- Muntean Eugen
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- Abstract:
- Inherited thrombophilia has been suggested as a cause of Legg-Calvé-Perthes disease in up to 75% of patients. This prevalence seems high compared to the prevalence of inherited thrombophilia in other thrombotic disorders (average, 30%). Therefore, we investigated 44 patients with Legg-Calvé-Perthes disease for antithrombin-III, protein-C, and protein-S deficiency and activated protein C (APC) resistance. Three (6.8%) of our patients were positive for APC resistance, and one patient (2.2%) showed deficiency of protein-C activity. Our results suggest that inherited thrombophilia is not associated with avascular necrosis of the femoral head (Legg-Calvé-Perthes disease).
- Find related publications in this database (using NLM MeSH Indexing)
- Activated Protein C Resistance - complications
- Adolescent - complications
- Adult - complications
- Antithrombin III - analysis
- Child - analysis
- Child, Preschool - analysis
- Female - analysis
- Humans - analysis
- Legg-Perthes Disease - blood
- Male - blood
- Protein S Deficiency - complications
- Thrombophilia - complications
- Find related publications in this database (Keywords)
- inherited thrombophilia
- Legg-Calve-Perthes disease