Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Gilli, R; Truschnig-Wilders, M; Beaufort, F; Lanzer, G.
Quality control of blood components by means of flow cytometers
Beitr Infusionsther Transfusionsmed. 1994; 32: 394-396.
PubMed
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Lanzer Gerhard
- Truschnig-Wilders Martini
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Abstract:
- Small numbers of leukocytes cannot be counted by automated methods. So we performed fluorescent staining of leukocyte DNA and analyzed 50 samples of single-donor PC by FACS. In 72% of these PC we found white blood cells (WBC) < 5/microliter = WBC < 10(6)/U. Nevertheless we do filter our PC. Should fresh frozen plasma (FFP) be irradiated for immunocompromised patients to prevent TA-GvHD? To evaluate the number and distribution of WBC in FFP we stained WBC with moAb and performed FACS analyses. We found WBC 7.164 +/- 5.66 x 10(6)/U, lymphocytes, 3.032 +/- 3.66 x 10(6)/U and T lymphocytes 2.135 +/- 2.02 x 10(6)/U. According to these data it should be considered to irradiate FFP for immunocompromised patients.
- Find related publications in this database (using NLM MeSH Indexing)
- Blood Donors -
- Blood Platelets -
- English Abstract -
- Flow Cytometry - methods
- Humans - methods
- Leukapheresis - standards
- Leukocytes - standards
- Lymphocytes - standards
- Plateletpheresis - standards
- Quality Control - standards
- T-Lymphocytes - standards