Medizinische Universität Graz - Research portal
Selected Publication:
Hollwarth, ME; Smith, M; Kvietys, PR; Granger, DN.
Esophageal blood flow in the cat. Normal distribution and effects of acid perfusion.
Gastroenterology. 1986; 90(3):622-627
Doi: 10.1016/0016-5085(86)91116-9
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- Leading authors Med Uni Graz
- Höllwarth Michael
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- Abstract:
- The radioactive microsphere technique was used to estimate blood flow to different regions of the esophagus and to adjacent regions of the stomach before and after perfusion of the esophagus with hydrochloric acid (pH 1.5) for 5 min. Under resting conditions total blood flow, as well as blood flow to the mucosal-submucosal layer and the muscular layer, to both sphincters was significantly higher than to the esophageal body. Blood flow to the adjacent regions of the stomach was significantly higher than esophageal blood flow. Acid perfusion resulted in a large increase in total blood flow in both sphincters and the lower esophageal body. Gastric blood flow was not altered by acid perfusion. The esophageal hyperemia resulted primarily from an increase in blood flow to the muscular layer; mucosal-submucosal blood flow was increased only in the lower esophageal sphincter. The present study indicates that short periods (5 min) of gastroesophageal reflux may increase esophageal blood flow.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Cats -
- Esophagogastric Junction - blood supply
- Esophagus - blood supply
- Gastric Acid - secretion
- Gastroesophageal Reflux - physiopathology
- Hydrochloric Acid - pharmacology
- Microspheres -
- Radioisotopes - diagnostic use
- Regional Blood Flow -
- Stimulation, Chemical -
- Stomach - blood supply
- Time Factors -