Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Wedrich, A; Menapace, R.
Effect of carbachol on intraocular pressure in small-incision cataract surgery.
Doc Ophthalmol. 1992; 80(4):301-307
Doi: 10.1007/BF00154377
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Wedrich Andreas
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- Abstract:
- Sixty patients, who underwent phacoemulsification and implantation of a folded polyHema intraocular lens were assigned to two groups. Following wound closure 0.5 ml of 0.01% carbachol or balanced salt solution was instilled into the anterior chamber. Healon was used in all eyes but evacuated from the capsular bag behind the intraocular lens and the anterior chamber. Intraocular pressure was measured the day before as well as 6 and 18 hours postoperatively. At 6 hours the mean change of intraocular pressure from baseline was -2.8 +/- 5.3 mmHg in the carbachol group compared with +4.7 +/- 8.0 mmHg in the BSS group (p < 0.0001). At 18 hours the mean change from baseline was -3.0 +/- 4.6 mmHg in the treatment group and +2.3 +/- 8.5 in the control group (p < 0.0001). Intraocular pressure exceeding 25 mmHg at 6 hours was observed in 8 (27%) eyes of the control group but none of the treatment group. At 18 hours 4 (13%) eyes of the control group and 1 (3%) of the carbachol group still had an increase of intraocular pressure. Summarizing our results we conclude that the effect of Healon on the postoperative intraocular pressure is successfully counteracted by its aspiration from the capsular bag and the anterior chamber, especially when carbachol is used for intraoperative miosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Anterior Chamber - drug effects
- Carbachol - therapeutic use
- Cataract Extraction - therapeutic use
- Female - therapeutic use
- Humans - therapeutic use
- Hyaluronic Acid - therapeutic use
- Intraocular Pressure - drug effects
- Lenses, Intraocular - drug effects
- Male - drug effects
- Ocular Hypertension - prevention and control
- Postoperative Complications - prevention and control
- Prospective Studies - prevention and control
- Suture Techniques - prevention and control
- Find related publications in this database (Keywords)
- CARBACHOL
- INTRAOCULAR PRESSURE
- POLYHEMA INTRAOCULAR LENS
- SMALL-INCISION CATARACT SURGERY
- SODIUM HYALURONATE