Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ansari-Shahrezaei, S; Ergun, E; Chong, R; Tufail, A; Wedrich, A; Stur, M.
Magnification-corrected photodynamic therapy.
Graefes Arch Clin Exp Ophthalmol. 2007; 245(3):333-337
Doi: 10.1007/s00417-006-0419-y
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- Führende Autor*innen der Med Uni Graz
- Ansari Shahrezaei Siamak
- Co-Autor*innen der Med Uni Graz
- Wedrich Andreas
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- Abstract:
- To present a method for performing photodynamic therapy (PDT) with a constant predictable light fluence based on actual laser spot magnification. A calibrated Gullstrand-type model eye with a scale of half circles in the centre of the artificial fundus was used for this study. The axial length of the model eye was set to different values ranging from 20 to 31 mm, and the actual laser spot magnification of four indirect condensing laser lenses were determined using a PDT laser unit. Equations for determining the actual laser spot magnification were calculated for each laser lens. The total change in laser spot magnification from hyperopia (axial length 20 mm) to myopia (axial length 31 mm) was -20% to +24.8% for Mainster Standard lens (Ocular Instruments Inc, Bellevue, Washington, USA), -15.7% to +27.7% for Mainster Wide Field lens (Ocular Instruments Inc), -16.3% to +33.1% for Volk Transequator lens (Volk Optical Inc, Mentor, Ohio, USA), and -19.2% to +24.4% for Volk PDT Laser lens (Volk Optical Inc). Axial length of the eye has a considerable effect on PDT laser spot magnification when an indirect laser lens is used. By calculating the actual laser spot magnification in conjunction with knowledge of the true greatest linear dimension of the neovascular lesion, the clinician may be able to deliver a constant predictable amount of light fluence to the fundus independent of the axial length of the PDT treating eye.
- Find related publications in this database (using NLM MeSH Indexing)
- Choroidal Neovascularization - drug therapy
- Humans -
- Hyperopia - complications
- Lasers -
- Models, Biological -
- Myopia - complications
- Photochemotherapy - methods
- Photosensitizing Agents - therapeutic use
- Porphyrins - therapeutic use
- Find related publications in this database (Keywords)
- photodynamic therapy
- light fluence
- choroidal neovascularization