Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pizzichetta, MA; Massone, C; Soyer, HP.
Regression of atypical nevus: an anecdotal dermoscopic observation.
Dermatol Surg. 2006; 32(10):1274-1277
Doi: 10.1111/j.1524-4725.2006.32290.x
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Massone Cesare
- Soyer Hans Peter
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- Abstract:
- BACKGROUND: Clark nevi (atypical melanocytic nevi) can be considered as risk markers and potential precursors of melanoma. The authors report on the morphologic changes of an atypical nevus by dermoscopic follow-up examination over a 7-year period. CASE REPORT: A 43-year-old man had a brown macule on his back, sized 5 mm, with an irregular shape, clinically and dermoscopically diagnosed as an equivocal melanocytic lesion. Dermoscopically during the initial examination, a predominant reticular pattern with peripheral eccentric hyperpigmentation in the lower portion of the lesion could be seen. After 7 months, the area of peripheral eccentric hyperpigmentation had regressed, and after 4.5 years the atypical pigment network had almost disappeared. After 7 years of follow-up, a diffuse area of hypopigmentation and a residual light brown pigmentation were detectable. The histopathologic diagnosis was consistent with an atypical junctional nevus with regression with features of a Clark nevus. CONCLUSION: Based on our observation, even a dermoscopically atypical nevus may undergo regression as documented by long-term dermoscopic follow-up.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Back -
- Dermoscopy -
- Disease Progression -
- Follow-Up Studies -
- Humans -
- Male -
- Neoplasm Regression, Spontaneous - pathology
- Nevus - pathology
- Skin Neoplasms - pathology