Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sommer, C; Urlesberger, B; Maurer-Fellbaum, U; Kutschera, J; Müller, W.
Neurodevelopmental outcome at 2 years in 23 to 26 weeks old gestation infants.
Klin Padiatr. 2006; 219(1):23-29
Doi: 10.1055/s-2006-921341
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Sommer Constanze
- Urlesberger Berndt
- Co-Autor*innen der Med Uni Graz
- Maurer-Fellbaum Ute
- Müller Wilhelm
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- Abstract:
- Background: Assessment of neurologic and developmental outcome at 2 years age of infants with gestational age (GA) <27weeks, born between 1996-2001. Patients: A total of 110 live-born preterm infants with GA <27weeks. Methods: Main outcome criterions: Neurologic examination (according to Touwen) and classification of cerebral palsy by using the Gross Motor Function Classification System (GMFCS) at the corrected age of 1 and 2 years; assessment of mental and psychomotor development by using the Griffith Mental Development scales at the corrected age of 2 years; growth assessment at birth, I and 2 years. Results: Mortality was 52%. Regular follow up was performed in 48 (91%) of the 53 surviving infants. Neurologic outcome: at 1 year age: 2% nonambulant cerebral palsy, 25% mild neurologic signs and 73% normal; at 2 years age: 4% nonambulant cerebral palsy, 2% ambulant cerebral palsy, 4% mild neurologic signs and 90% normal neurology. Developmental outcome at 2 years age: 40% DQ>-1 SD, 6% DQ between -1 SD and -2 SD (mild delay), 35% DQ between -2 SD and -3 SD (moderate delay) and 19% DQ<-3 SD (severe delay). Overall disability was found in 64%, severe disability in 27% of the infants. Profound growth failure in weight and head circumference <3rd centile at 2 years age was recorded in 39 and 19% of the infants, respectively. Conclusion: Developmental delay is very common in preterm infants < 27 GA and exceeds the number of neurological disabilities (including cerebral palsy).
- Find related publications in this database (using NLM MeSH Indexing)
- Body Weight -
- Brain Damage, Chronic - diagnosis
- Cephalometry -
- Cerebral Palsy - diagnosis
- Child, Preschool -
- Comorbidity -
- Developmental Disabilities - diagnosis
- Disabled Children - classification
- Female -
- Follow-Up Studies -
- Humans -
- Infant -
- Infant, Extremely Low Birth Weight -
- Infant, Newborn -
- Infant, Premature, Diseases - diagnosis
- Male -
- Neurologic Examination -
- Pregnancy -
- Pregnancy Trimester, Second -
- Survival Rate -
- Find related publications in this database (Keywords)
- extremely preterm infants
- neonatal morbidity
- neurodevelopmental outcome