Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Klingenberg, HG; Porta, J; Egger, G; Esterbauer, H; Kramer, G; Sadjak, A.
Adrenaline application by intraperitoneal depot capsule -- effects in the heart (author's transl)
Exp Pathol (Jena). 1977; 13(6): 302-312.
Doi: 10.1016/S0014-4908(77)80017-3
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- Co-Autor*innen der Med Uni Graz
- Porta Sepp
- Sadjak Anton
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- Abstract:
- An intraperitoneal depot capsule was developed to improve the hitherto used in vivo test methods for chronic action of water soluble substances (repeated injections or permanent infusion which immobilizes the experimental animals). The capsule allows free movement of the animal and guarantees long-term continuous output of the substance. The effectiveness of the capsule was examined using adrenaline as test substance. In these experiments the maximum period of effectiveness and the consequences of permanent occupation of the receptors due to continued supply of adrenaline were studied.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Drug Implants -
- English Abstract -
- Epinephrine - administration and dosage
- Heart - drug effects
- Myocardium - pathology
- Organ Size - pathology
- Peritoneum - pathology
- Pulse - pathology
- Rats - pathology
- Time Factors - pathology