Medizinische Universität Graz - Research portal
Selected Publication:
Vadon, P; Rehak, P.
Comparison of the analgesic effect of nicomorphine in two different solutions (author's transl)
Wien Med Wochenschr. 1979; 129(8): 217-220.
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- Co-authors Med Uni Graz
- Rehak Peter
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- Abstract:
- The analgesic effect of nicomorphine in two different solutions was tested in 120 patients after cholecystectomy. The patients were divided into three groups: group I was given nicomorphine diluted with water, group II nicomorphine diluted with propylenglykol, group III propylenglykol alone. The degree of pain sensation was determined by interrogation. Pulse, respiratory rate, blood pressure as well as capillary pO2 and pCO2 were measured 10 and 30 minutes after medication. No difference in pain relief could be established in the two groups receiving nicomorphine. Respiratory depression with a significant decrease of respiratory rate together with an increase of pCO2 was observed in the two nicomorphine groups. In the placebo group there was no significant change in the tested parameters. A small decrease of pO2 was observed in all patients after laparotomy.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Blood Pressure - drug effects
- Carbon Dioxide - blood
- Cholecystectomy - blood
- Comparative Study - blood
- Drug Evaluation - blood
- English Abstract - blood
- Female - blood
- Humans - blood
- Injections, Intramuscular - blood
- Male - blood
- Middle Aged - blood
- Morphine Derivatives - administration and dosage
- Nicotinic Acids - administration and dosage
- Oxygen - blood
- Pain, Postoperative - drug therapy
- Propylene Glycols - drug therapy
- Pulse - drug effects
- Respiration - drug effects
- Solutions - drug effects
- Water - drug effects