Medizinische Universität Graz - Research portal
Selected Publication:
Müllner-Eidenböck, A; Amon, M; Schauersberger, J; Kruger, A; Abela, C; Petternel, V; Zidek, T.
Cellular reaction on the anterior surface of 4 types of intraocular lenses.
J Cataract Refract Surg. 2001; 27(5):734-740
Doi: 10.1016/S0886-3350(01)00846-X
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-authors Med Uni Graz
- Gasser-Steiner Vanessa
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- PURPOSE: To assess the cellular reaction on the anterior surface of 4 types of foldable intraocular lenses (IOLs). SETTING: Department of Ophthalmology, University Hospital of Vienna, Vienna, Austria. METHODS: One hundred eyes scheduled for cataract surgery were prospectively randomized into 4 groups of 25 eyes each using random number tables. Group 1 received a Hydroview IOL (Bausch & Lomb), Group 2 an AcrySof IOL (Alcon), Group 3 a MemoryLens IOL (ORC), and Group 4 a CeeOn 920 IOL (Pharmacia). Patients were examined 1, 3, 7, 30, 90, and 180 days postoperatively. Postoperative biomicroscopic examinations were done with a slitlamp, and a specular microscope was used to document the presence of cell deposits and identify areas with the highest density of cells. RESULTS: The local tissue response revealed 2 patterns: a nonspecific foreign-body reaction to the IOL (small round, fibroblast-like, epithelioid, and giant cells) and a lens epithelial cell (LEC) reaction. The highest incidence of LECs was in the Hydroview group, in which LECs were present on 81.8% of lenses 180 days postoperatively. During the first postoperative days, small round and fibroblast-like cells were found on all IOLs. From 7 days on, the incidence and density of these cells were less severe in the Hydroview and CeeOn 920 groups. After several weeks, epithelioid cells and foreign-body giant cells were seen on some IOLs. These cells appeared more often on AcrySof, MemoryLens, and CeeOn IOLs. CONCLUSION: This study found IOL-related differences in cellular reaction after cataract surgery. The incidence of a nonspecific foreign-body reaction to 4 IOLs is consistent with the results of previous studies. The incidence of LECs was highest in the Hydroview group and lowest in the AcrySof group. The CeeOn 920 group had the lowest incidence of all types of cells.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Cell Count -
- Comparative Study -
- Epithelial Cells - pathology
- Eye Foreign Bodies - diagnosis
- Female - diagnosis
- Fibroblasts - pathology
- Foreign-Body Reaction - diagnosis
- Giant Cells - pathology
- Humans - pathology
- Incidence - pathology
- Lens Implantation, Intraocular - pathology
- Lenses, Intraocular - adverse effects
- Male - adverse effects
- Microscopy - methods
- Phacoemulsification - methods
- Prospective Studies - methods