Medizinische Universität Graz - Research portal
Selected Publication:
Petternel, V; Findl, O; Kruger, A; Schauersberger, J; Amon, M.
Effect of tropicamide on aqueous flare before and after cataract surgery.
J Cataract Refract Surg. 2000; 26(3):382-385
Doi: 10.1016/S0886-3350(99)00404-6
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- Gasser-Steiner Vanessa
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- Abstract:
- PURPOSE: To examine the effect of tropicamide on flare intensity under phakic and pseudophakic conditions and to differentiate between the possible mechanisms of action of tropicamide on aqueous flare. SETTING: Department of Ophthalmology, Vienna General Hospital, University of Vienna, Vienna, Austria. METHODS: In this prospective study, aqueous flare was measured with the laser flare-cell meter in 20 eyes of 20 patients with age-related cataract enrolled for cataract surgery. Measurements were performed before and 30, 90, and 180 minutes after pupil dilation with tropicamide 0.5%. This measurement was performed in the phakic eye on the day before surgery and in the pseudophakic eye on postoperative days 1, 3, 7, and 28. RESULTS: After tropicamide instillation, aqueous flare decreased preoperatively and on all postoperative days. There was a continuous flare decrease until 3 hours after instillation, reaching a maximum decrease of about 30%. Pupil diameter reached its maximum after 30 minutes. CONCLUSION: Tropicamide significantly decreased aqueous flare, seemingly by pharmacological means, not volumetric changes. The time between drug application and measurement should be kept constant.
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- Aqueous Humor - cytology
- Cataract Extraction - adverse effects
- Cell Count - drug effects
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