Selected Publication:
Georgopoulos, M; Menapace, R; Findl, O; Petternel, V; Kiss, B; Rainer, G.
After-cataract in adults with primary posterior capsulorhexis: comparison of hydrogel and silicone intraocular lenses with round edges after 2 years.
J Cataract Refract Surg. 2003; 29(5):955-960
Doi: 10.1016/S0886-3350(02)01814-X
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- Co-authors Med Uni Graz
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Gasser-Steiner Vanessa
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- Abstract:
- PURPOSE: To evaluate the potential of primary posterior continuous curvilinear capsulorhexis (PCCC) to prevent after-cataract 2 years after surgery and perform a bilateral comparison of 2 intraocular lens (IOL) materials, silicone and hydrogel. SETTING: Department of Ophthalmology, University of Vienna, Medical School, Vienna, Austria. METHODS: In this randomized patient- and examiner-masked study, 37 patients (74 eyes) with age-related cataract had bilateral small-incision cataract surgery with PCCC. Randomly, 1 eye received a hydrogel IOL and the contralateral eye, a silicone IOL. Both IOLs had open-loop haptics and a round-edged optic. Standardized digital retroillumination photographs were taken 1 day and 1, 6, 12, and 24 months after surgery to evaluate development of after-cataract on the anterior and posterior capsules by subjective grading. Opacification of the PCCC area was also objectively evaluated using new software. RESULTS: Twenty-nine patients (58 eyes) completed the 2-year follow-up. Partial closure with ongrowth at the edge of the PCCC was found in 55% in the hydrogel group and 28% in the silicone group. Total closure of the PCCC was observed in 3 eyes, 2 in the hydrogel group and 1 in the silicone group. CONCLUSION: Ongrowth onto the PCCC area was dependent on IOL material. Because of less ongrowth and more fibrotic after-cataract with silicone IOLs, the efficacy of the PCCC was higher in this group.
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Aged -
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Aged, 80 and over -
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Capsulorhexis - methods
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Cataract - diagnosis
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Comparative Study - diagnosis
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Double-Blind Method - diagnosis
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Epithelial Cells - pathology
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Female - pathology
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Humans - pathology
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Hydrogel - pathology
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Laser Surgery - pathology
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Lens Capsule, Crystalline - pathology
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Lens Implantation, Intraocular - pathology
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Lenses, Intraocular - adverse effects
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Male - adverse effects
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Middle Aged - adverse effects
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Postoperative Complications - adverse effects
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Prospective Studies - adverse effects
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Prosthesis Design - adverse effects
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Silicone Elastomers - adverse effects