Medizinische Universität Graz - Research portal
Selected Publication:
Gücer, F; Reich, O; Tamussino, K; Bader, AA; Pieber, D; Schöll, W; Haas, J; Petru, E.
Concomitant endometrial hyperplasia in patients with endometrial carcinoma.
Gynecol Oncol. 1998; 69(1):64-68
Doi: 10.1006/gyno.1997.4911
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-authors Med Uni Graz
- Bader Arnim
- Haas Josef
- Petru Edgar
- Pieber Doris
- Reich Olaf
- Schöll Wolfgang
- Tamussino Karl
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- OBJECTIVES: The aim of this study was to compare the histopathologic features and prognosis of patients with endometrial carcinoma with and without concomitant hyperplasia. METHODS: Histologic slides of the surgical specimens of 214 consecutive patients who underwent surgery as primary treatment for endometrial carcinoma from 1985 through 1991 were reviewed. RESULTS: Ninety-two of the 214 patients (43%) with endometrial carcinoma had concomitant endometrial hyperplasia. Patients with endometrial carcinoma with hyperplasia were significantly younger than those without hyperplasia (mean age 62 +/- 10 vs 65 +/- 9 years, P < 0.05). Carcinomas associated with hyperplasia were better differentiated and of lower surgical stage. By univariate analysis the frequency of recurrence was significantly lower (4% vs 17%, P < 0.004) and the estimated 5-year survival rate significantly higher (96% vs 85%, P < 0.01) in patients with endometrial carcinoma with concomitant hyperplasia. However, in multivariate analysis the presence of endometrial hyperplasia was not an independent prognostic factor and the 5-year survival rates of patients with or without hyperplasia did not differ significantly in any surgical stage. CONCLUSION: The presence or absence of concomitant endometrial hyperplasia is strongly correlated with the surgical stage of endometrial carcinoma.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenocarcinoma - pathology
- Adenocarcinoma, Clear Cell - pathology
- Age Factors - pathology
- Aged - pathology
- Carcinoma, Adenosquamous - pathology
- Cystadenocarcinoma, Papillary - pathology
- Endometrial Hyperplasia - pathology
- Endometrial Neoplasms - pathology
- Female - pathology
- Humans - pathology
- Metaplasia - pathology
- Middle Aged - pathology
- Neoplasm Staging - pathology
- Prognosis - pathology
- Recurrence - pathology
- Retrospective Studies - pathology
- Survival Analysis - pathology
- Find related publications in this database (Keywords)
- Endometrial Carcinoma
- Hyperplasia
- Prognosis
- Surgical Stage