Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Trummer, H; Habermann, H; Haas, J; Pummer, K.
The impact of cigarette smoking on human semen parameters and hormones.
Hum Reprod. 2002; 17(6):1554-1559
Doi: 10.1093%2Fhumrep%2F17.6.1554
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- Co-Autor*innen der Med Uni Graz
- Haas Josef
- Habermann Helga
- Pummer Karl
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- Abstract:
- BACKGROUND: In this prospective study, semen parameters and hormone concentrations of infertile smokers were compared with infertile non- and ex-smokers. We also determined how many men with idiopathic infertility would stop smoking in an attempt to improve their fertility. METHODS: 1104 men (517 non-smokers, 109 ex-smokers and 478 smokers) with infertility for at least 1 year were evaluated. Evaluation included medical history, physical examination, hormone analysis and two semen analyses. Prior to the second semen analysis, smokers were urged to quit smoking. RESULTS: Smokers were significantly younger (P < 0.001), had significantly more round cells in their ejaculates (P = 0.003), and the percentage of ejaculates with > 1 x 10(6)/ml leukocytes was higher in smokers (P < 0.001). Increased free and total serum testosterone (P < 0.001) and decreased prolactin levels (P < 0.001) were found in smokers. No differences were found between non-smokers and ex-smokers. Only 23.1% of the smokers versus 46% non-smokers (P < 0.001) returned for a second semen analysis, 14 of whom reduced and 15 of whom quit smoking completely. Testosterone levels were significantly lower in those who were able to stop or reduce smoking (P < 0.001). CONCLUSIONS: Smoking does not affect conventional semen parameters, but significantly increases round cells and leukocytes. Only a few idiopathic infertile smokers were able to quit smoking.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Humans -
- Infertility, Male - blood
- Male - blood
- Prolactin - blood
- Prospective Studies - blood
- Semen - cytology
- Smoking - adverse effects
- Smoking Cessation - adverse effects
- Sperm Count - adverse effects
- Sperm Motility - adverse effects
- Spermatozoa - abnormalities
- Testosterone - blood
- Find related publications in this database (Keywords)
- hormones
- human semen
- male fertility
- smoking
- withdrawal