Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schwarz, G; Litscher, G; Tscheliessnigg, KH; Pfurtscheller, G; Fuchs, G; Zwiener, U.
Computer-assisted neurovegetative monitoring in patients after heart transplantation.
Biomed Tech (Berl). 1994; 39(5):105-112
Doi: 10.1515/bmte.1994.39.5.105
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- Führende Autor*innen der Med Uni Graz
- Schwarz Gerhard
- Co-Autor*innen der Med Uni Graz
- Fuchs Gottfried
- Litscher Gerhard
- Tscheliessnigg Karlheinz
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- Abstract:
- The effects of orthotopic heart transplantation on spontaneous fluctuations of the respiration rate and heart rate were studied with a computer-assisted system for neurovegetative monitoring in 22 patients (mean age +/- SD: 48.7 +/- 9.4 years) 19.5 +/- 14.4 months after transplantation. The control group consisted of 12 healthy volunteers (mean age +/- SD: 38.7 +/- 6.6 years). The mean (+/- SE) respiratory rate was higher in the transplantation group than in the control group (17.7 +/- 0.8/min vs. 14.6 +/- 1.1 breaths/min, P < 0.2). The mean variability of the respiratory rate was smaller in the transplant patients than in the controls (3.7 +/- 0.3 vs. 2.8 +/- 0.4, P < 0.2). The heart rate variability coefficient in the patients after transplantation was lower than that in the controls (1.3 +/- 0.1% vs. 6.9 +/- 0.5%, P < 0.001). Spectral analysis of heart rate variability showed a smaller decrease of variability of respiration (P < 0.05) than of blood pressure regulation (P < 0.001) or of the angiotensin-renin system (P < 0.001). A separate group of 7 transplant patients (mean age 51.0 +/- 7.7 years) had activated cardiac pacemakers and thus no spontaneous physiologic heart rate oscillations. The variability of the respiratory rate in these patients was lower than in the other 22 transplant patients (1.8 +/- 0.2 vs. 3.7 +/- 0.3, P < 0.001). The data provided by multiparametric neurovegetative monitoring support the evaluation of complex regulatory mechanisms of respiratory and cardiovascular function and their adaptability after orthotopic heart transplantation.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Autonomic Nervous System - physiopathology
- Female - physiopathology
- Follow-Up Studies - physiopathology
- Heart Rate - physiology
- Heart Transplantation - physiology
- Humans - physiology
- Male - physiology
- Microcomputers - physiology
- Middle Aged - physiology
- Monitoring, Physiologic - instrumentation
- Postoperative Complications - physiopathology
- Respiration - physiology
- Signal Processing, Computer-Assisted - instrumentation
- Find related publications in this database (Keywords)
- Neurovegetative Monitoring
- Orthotopic Heart Transplantation
- Respiratory Rate Variability
- Heart Rate Variability