Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
El Shabrawi-Caelen, L; Soyer, HP; Schaeppi, H; Cerroni, L; Schirren, CG; Rudolph, C; Kerl, H.
Genital lentigines and melanocytic nevi with superimposed lichen sclerosus: a diagnostic challenge.
J AMER ACAD DERMATOL. 2004; 50(5): 690-694.
Doi: 10.1016/j.jaad.2003.09.034
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Führende Autor*innen der Med Uni Graz
- El-Shabrawi-Caelen Laila
- Soyer Hans Peter
- Co-Autor*innen der Med Uni Graz
- Ambros-Rudolph Christina
- Cerroni Lorenzo
- Kerl Helmut
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- BACKGROUND: Benign pigmented lesions of the genitalia, such as genital lentigines and melanocytic nevi, often show clinical and histopathologic features highly suggestive of malignant melanoma (MM). Superimposed changes of lichen sclerosus (LS) may cause real concern and lead to an erroneous diagnosis of MM. OBJECTIVE: This study was performed to assess clinicopathologic characteristics of genital lentigines and melanocytic nevi with associated LS. METHODS: We performed a retrospective review of 5 cases. RESULTS: Histopathologic sections of the 2 cases of genital lentigines with concurrent changes of LS showed a lichenoid lymphocytic infiltrate and pigment incontinence with melanophages in a fibrosed papillary dermis, features reminiscent of completely regressed MM. The 3 cases of genital melanocytic nevi and superimposed LS were sharply circumscribed, relatively symmetric, but revealed confluent nests varying in size and shape and pagetoid upward spread of melanocytic nests and single melanocytes. Changes of LS extended beyond the melanocytic proliferation. CONCLUSION: Genital lentigines and melanocytic nevi with associated LS may show features that mimic MM.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Child -
- Female -
- Humans -
- Lentigo - complications
- Lichen Sclerosus et Atrophicus - complications
- Male - complications
- Middle Aged - complications
- Nevus, Pigmented - complications
- Penile Diseases - diagnosis
- Penile Neoplasms - complications
- Vulvar Diseases - diagnosis
- Vulvar Neoplasms - complications