Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Resch, B; Gusenleitner, W; Müller, W.
The impact of respiratory syncytial virus infection: a prospective study in hospitalized infants younger than 2 years.
INFECTION. 2002; 30(4): 193-197.
Doi: 10.1007/s15010-002-2122-1
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Resch Bernhard
- Co-Autor*innen der Med Uni Graz
- Müller Wilhelm
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- Abstract:
- Background: We analyzed the influence of respiratory syncytial virus (RSV) on the clinical course and management of infants hospitalized due to viral upper and Lower respiratory tract infections (U/LRTI). Patients and Methods: Infants younger than 2 years were prospectively tested for RSV infection by antigen detection in nasopharyngeal aspirates between November 1999 and October 2000. Results: Of 281 infants hospitalized during the study period, 58 (21%) tested RSV positive. Seasonal distribution of RSV infections showed a peak in March (45% of all U/LRTI). Infants with RSV infection (12% were preterm, 5% had congenital heart disease) were younger (p < 0.001), had more severe U/LRTI (p < 0.001), Longer hospitalizations (p < 0.001), more days with oxygen requirement (p < 0.001) and respiratory support (p = 0016) and more frequent requirements for bronchoditators (p = 0.002) and corticosteroids (p = 0.02). Conclusion: RSV contributed to prolonged hospitalizations and more severe clinical courses of disease both in very young term and preterm infants.
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- Hospitalization -
- Humans -
- Incidence -
- Infant -
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- Respiratory Syncytial Virus Infections - drug therapy Respiratory Syncytial Virus Infections - epidemiology Respiratory Syncytial Virus Infections - pathology
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- respiratory syncytial virus
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