Gewählte Publikation:
Homann, CN; Suppan, K; Homann, B; Crevenna, R; Ivanic, G; Ruzicka, E.
Driving in Parkinson's disease - a health hazard?
J Neurol. 2003; 250(12):1439-1446
Doi: 10.1007/s00415-003-0239-5
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
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Homann Carl
- Co-Autor*innen der Med Uni Graz
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Suppan Klaudia
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- Abstract:
- BACKGROUND: The driving safety of Parkinson's disease (PD) patients has lately been questioned after several authors reported road accidents caused by sleep attacks in PD patients on dopaminergic medication. OBJECTIVES: To determine 1) whether PD patients in general and those on dopaminergic medication in particular are especially prone to cause severe road accidents and 2) whether there are PD symptoms or dopaminergic side effects with the potential to compromise driving safety. DATA SOURCE: Relevant articles were identified by electronic search of biomedical databases (1966-2002: MEDLINE, EMBASE, PASCAL, PUBMED), the Cochrane Controlled Trials Register, and reference lists of located articles. RESULTS: Despite frequent occurrence of potentially hazardous dopaminergic side effects (2-57 %) and disabling parkinsonian non-motor and motor disabilities (16-63 %), the two existing studies on accident rates suggest that PD patients are not more prone to cause road accidents than the rest of the population. Five further reports including 1346 patients and focusing on dopaminergically induced sleep attacks provided comparably low accident figures (yearly incidence: 0%-2%). Because of low figures meta-analysis was intended but finally deemed inappropriate as the methodology of included studies varied greatly and was frequently flawed. CONCLUSION: Further prospective community-based well designed studies on accident risk in PD patients are needed to provide evidence based driving recommendations.
- Find related publications in this database (using NLM MeSH Indexing)
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Accidents, Traffic - statistics and numerical data
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Antiparkinson Agents - adverse effects
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Automobile Driving - adverse effects
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Disorders of Excessive Somnolence - etiology
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Dopamine Agents - adverse effects
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Humans - adverse effects
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Motor Activity - drug effects
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Parkinson Disease - drug therapy
- Find related publications in this database (Keywords)
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driving
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car accidents
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Parkinson's disease
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sleep attacks