Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Khoschsorur, G; Fruehwirth, F; Zelzer, S.
Isocratic high-performance liquid chromatographic method with ultraviolet detection for simultaneous determination of levels of voriconazole and itraconazole and its hydroxy metabolite in human serum.
ANTIMICROB AGENTS CHEMOTHER. 2005; 49(8): 3569-3571.
Doi: 10.1128/AAC.49.8.3569-3571.2005
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- Führende Autor*innen der Med Uni Graz
- Khoschsorur Gholamali
- Co-Autor*innen der Med Uni Graz
- Zelzer Sieglinde
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- Abstract:
- A simple, specific method is presented for simultaneous determination of voriconazole and itraconazole and its metabolite, hydroxyitraconazole, in human serum using one-step liquid-liquid extraction and high-performance liquid chromatography. Linearity tests ranged from 0.1 to 8.0 microg/ml; the minimum detectable concentration was 0.03 microg/ml.
- Find related publications in this database (using NLM MeSH Indexing)
- Antifungal Agents - blood
- Chromatography, High Pressure Liquid - blood
- Humans - blood
- Itraconazole - analogs and derivatives
- Pyrimidines - blood
- Reproducibility of Results - blood
- Sensitivity and Specificity - blood
- Triazoles - blood
- Ultraviolet Rays - blood