Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hiti, K; Walochnik, J; Maria Haller-Schober, E; Faschinger, C; Aspöck, H.
Efficacy of contact lens storage solutions against different acanthamoeba strains.
Cornea. 2006; 25(4):423-427
Doi: 10.1097/01.ico.0000214204.22200.7f
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Hiti Klaus
- Co-Autor*innen der Med Uni Graz
- Faschinger Christoph
- Haller-Schober Eva-Maria
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- Abstract:
- Purpose: This study was undertaken in order to determine the susceptibility of acanthamoebae to various contact lens disinfecting systems, with respect to type of disinfectant and exposure time. Methods: Ten contact lens solutions, including one new system, were tested for their effectivities against cysts of three Acanthamoeba strains. Of main interest was ail incubation time of 8 hours (overnight disinfection) and cyst quantities of 103 and 104, respectively. Results: Boston (TM) Advance (polyaminopropyl biguanide 0.0005%, chlorhexidine 0,003%) for the storage of rigid gas permeable contact lenses destroyed the cysts of all strains at either concentration within one hour of exposure. Meni Care Plus (polyhexamethylene biguanide 0.0005%) also destroyed 103 cysts of all strains, however, 104 Cysts only of two strains within one hour; after an exposure time of 8 hours all cysts were killed. The disinfecting solutions for soft contact lenses did not kill 104 cysts of either strain after 8 hours of incubation time. Conclusion: Two of the tested contact lens solutions (the ones for rigid gas permeable lenses) destroyed the cysts of all strains. One of these, containing a combination of two amoebicidal ingredients even after only one hour of exposure time.
- Find related publications in this database (using NLM MeSH Indexing)
- Acanthamoeba - classification Acanthamoeba - drug effects Acanthamoeba - growth & development
- Animals -
- Biguanides - pharmacology
- Chlorhexidine - analogs & derivatives Chlorhexidine - pharmacology
- Contact Lens Solutions - pharmacology
- Contact Lenses, Hydrophilic -
- Disinfectants - pharmacology
- Disinfection - methods
- Drug Therapy, Combination -
- Equipment Contamination -
- Time Factors -
- Find related publications in this database (Keywords)
- Acanthamoeba
- disinfection
- contact lenses
- keratitis