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Zuberbier, T; Aberer, W; Burtin, B; Rihoux, JP; Czarnetzki, BM.
Efficacy of cetirizine in cholinergic urticaria.
ACTA DERMATO-VENEREOL 1995 75: 147-149.
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Co-authors Med Uni Graz: Aberer Werner
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Abstract:: In order to examine the efficacy of cetirizine in cholinergic urticaria, we studied 24 patients in a double-blind crossover design during 3-week treatment periods, with either 10 or 20 mg/d cetirizine or placebo. The placebo period was always placed in between the two verum treatments to allow for a washout of the drug. Evaluation of the patients' daily symptom scores based on itching, erythema and whealing showed a highly significant improvement (p < 0.01). The percentage of days with mild or no symptoms was also increased significantly with the drug (p < 0.05). Except for whealing (p < 0.05), no significant differences between the two dosages of cetirizine could be determined. Since antihistamines have previously been shown to be frequently unsatisfactory in the treatment of cholinergic urticaria, the present data are encouraging regarding the control of symptoms in this condition.
Find related publications in this database (using NLM MeSH Indexing): Adult -; Analysis of Variance -; Cetirizine - adverse effects; Cross-Over Studies - adverse effects; Double-Blind Method - adverse effects; Exertion - physiology; Female - physiology; Humans - physiology; Male - physiology; Treatment Outcome - physiology; Urticaria - drug therapy
Find related publications in this database (Keywords): ANTIHISTAMINE