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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Fritz, GA; Schoellnast, H; Deutschmann, HA; Quehenberger, F; Tillich, M.
Multiphasic multidetector-row CT (MDCT) in detection and staging of transitional cell carcinomas of the upper urinary tract.
Eur Radiol. 2006; 16(6):1244-1252
Doi: 10.1007/s00330-005-0078-0
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- Leading authors Med Uni Graz
- Fritz Gerald
- Co-authors Med Uni Graz
- Deutschmann Hannes
- Quehenberger Franz
- Schoellnast Helmut
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- Abstract:
- The aim of this study was to evaluate the potential of multiphasic multidetector-row CT (MDCT) in the detection and staging of transitional cell carcinomas (TCC) of the upper urinary tract. We performed a retrospective chart review of 39 consecutive patients with 41 histologically verified TCC of the renal pelvis and/or the ureter. The urinary tract was examined using MDCT performing unenhanced and contrast-enhanced scans during the corticomedullary (CMP), nephrographic (NP) and pyelographic phase (PP). Tumors were staged according to the TNM classification. MDCT and histopathological findings were correlated. The attenuation of the lesions was documented in Hounsfield units (HU). In MDCT, all 41 TCC--including two multicentric TCC--were detected. TCC confined to the organ (stage 0a-II) was correctly staged in 28/29 tumors (96.6%). Stage III-IV tumors were correctly staged in 8/12 patients (66.6%). Overall, MDCT was accurate in predicting pathologic TNM stage in 36/41 upper urinary tract TCC (87.8%). There was no significant difference of mean attenuation of TCC between CMP, NP and PP (P > 0.05). MDCT with its high spatial and temporal resolution is an accurate tool for detection TCC of the upper urinary tract, with 87.8% accuracy in predicting its stage.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Aged, 80 and over -
- Carcinoma, Transitional Cell - pathology Carcinoma, Transitional Cell - radiography
- Cohort Studies -
- Contrast Media -
- Female -
- Forecasting -
- Humans -
- Image Processing, Computer-Assisted - methods
- Kidney Cortex - radiography
- Kidney Medulla - radiography
- Kidney Neoplasms - pathology Kidney Neoplasms - radiography
- Kidney Pelvis - radiography
- Male -
- Middle Aged -
- Neoplasm Staging -
- Nephrons - radiography
- Radiographic Image Enhancement - methods
- Retrospective Studies -
- Tomography, X-Ray Computed - methods
- Ureteral Neoplasms - pathology Ureteral Neoplasms - radiography
- Urography -
- Find related publications in this database (Keywords)
- multiphasic multidetector row CT (MDCT)
- transitional cell carcinoma
- renal pelvis
- ureter
- upper urinary tract
- staging