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SHR Neuro Cancer Cardio Lipid Metab Microb

Stauber, RE; Stadlbauer, V.
Novel approaches for therapy of chronic hepatitis C.
J CLIN VIROL. 2006; 36(2): 87-94. Doi: 10.1016/j.jcv.2006.02.003
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Leading authors Med Uni Graz: Stauber Rudolf
Co-authors Med Uni Graz: Stadlbauer-Köllner Vanessa
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Abstract:: Currently available anti-HCV therapy is effective in only half of the patients and limited by side effects that often necessitate discontinuation. Therefore, new treatment strategies are being developed including (i) the optimization of current regimens, (ii) the use of additional agents working via novel mechanisms, and (iii) anti-fibrotic strategies. Many new antiviral compounds are now being studied in preclinical and clinical trials. This review will focus on drugs that have already entered the stage of phase 2 or phase 3 studies.
Find related publications in this database (using NLM MeSH Indexing): Antidepressive Agents - therapeutic use; Antiviral Agents - therapeutic use; Clinical Trials as Topic -; Erythropoietin - therapeutic use; Genome, Viral -; Hepacivirus - drug effects Hepacivirus - genetics; Hepatitis C, Chronic - complications Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - therapy; Humans -; Interferons - therapeutic use; Liver Cirrhosis - etiology Liver Cirrhosis - prevention and control; Protease Inhibitors - therapeutic use; Purine-Nucleoside Phosphorylase - antagonists and inhibitors Purine-Nucleoside Phosphorylase - chemistry Purine-Nucleoside Phosphorylase - therapeutic use; Pyrimidine Nucleosides - therapeutic use; Ribavirin - analogs and derivatives Ribavirin - chemistry Ribavirin - therapeutic use; Viral Hepatitis Vaccines - therapeutic use
Find related publications in this database (Keywords): chronic hepatitis C; interferons; protease inhibitors; polymerase inhibitors; immunomodulators